https://pubmed.ncbi.nlm.nih.gov/40336446/ [Interventional psychiatric procedures and novel substances for the treatment of affective disorders: An overview and outlook (Bacht, et al, 2025) #ketamine #mentalhealth #psychotherapy #ketaminetherapy #ketamineassistedpsychotherapy #psychedelics #psychedelictherapy #psychedelicassistedpsychotherapy #psychedelicresearch #ketamineassistedtherapy

Ketamine evokes acute behavioral effects via μ-opioid receptor expressing neurons of the central amygdala (Pomrenze, et al, 2025) https://pubmed.ncbi.nlm.nih.gov/40334963/ The CeA and MORs might be critical in triggering the cascade that leads to the broader network plasticity revealed by the recent mesoscale analysis brain network study #ketamine #neuroscience #ketaminetherapy #depression #mentalhealth #psychedelic #psychedelics #ketaamineassistedpsychotherapy

Spotlight: Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide + μ-opioid receptor? #ketamine #ketaminetherapy #psychedelic #psychedelics #psychedelicresearch #depression #mentalhealth #neuroscience #ketamineassistedpsychotherapy https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/

https://www.psychiatryonline.org/doi/10.1176/appi.ajp.20230751 Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression (Wall, et al, 2025) #psilocybin #psychedelic #psychedelics #depression #mentalhealth #psychedelicresearch

LSD for Anxiety and Depression: Worth the Trip? https://flip.it/71kFpz #psychedelic #psychedelics #lsd #psychotherapy #mentalhealth #psychedelicresearch #anxiety #depression Note— they still have not put together that #ketamine can be the blind in #psychedelicresearch And they still try to minimize the importance of the psychotherapy in medicine assisted psychotherapy. Glad this gets hi-lighted

https://pubmed.ncbi.nlm.nih.gov/40328099/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250507002646&v=2.18.0.post9+e462414 Can ketamine and other glutamate receptor modulators be considered entactogens? (Hu, et al, 2025) #ketamine #ketaminetherapy #psychedelic #psychedelics #neuroscience #mentalhealth #entactogen #glutamate

Psychedelic interventions for major depressive disorder in the elderly: Exploring novel therapies, promise and potential https://flip.it/a7TKDu (Tudorancea, et al, 2025) #psychedelics #psychedelic #depression #mentalhealth #psychedelicresearch

https://psychedelicmentalhealth.net/psychedelics-in-palliative-care-glass-oxford-university-press/ Pre-order: "Psychedelics in Palliative Care", Marcia Glass, Ed., Oxford University Press with contributions by Psychedelic Institute fellows, Michael DeMarco, PhD and Thaís Salles Araujo, MD on #ketamine, #psilocybin mushrooms in palliative care -- I'm so proud to have contributed to this, and dedicate it in memory of my dog Fen #psychedelics #psychedelic #palliativecare #ketaminetherapy #psychedelictherapy #ketamina

Only elites used hallucinogens in ancient Andes society https://arstechni.ca/FKsGg #forensicarchaeology #hallucinogens #anthropology #psychedelics #ethnobotany #Archeology #Science

https://www.pnas.org/doi/10.1073/pnas.2425125122 Pre-Hispanic ritual use of psychoactive plants at Chavín de Huántar, Peru (Rick, et al, 2025) #psychedelic #psychedelics #plantmedicine

Out-of-body experiences: interpretations through the eyes of those who live them (Moix, et al, 2025) #ketamine #consciousness #psychedelic #psychedelics #obe #outofbodyexperience https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1566679/full

#Colorado House Approves Senate-Passed #Psychedelics Bill To Allow Pardons And Implement Data-Tracking https://www.marijuanamoment.net/colorado-house-approves-senate-passed-psychedelics-bill-to-allow-pardons-and-implement-data-tracking/

Qualitative analysis of a patient's experience of ketamine-assisted psychotherapy for substance use disorder: Empirical synergies with twelve-step programs https://www.sciencedirect.com/science/article/pii/S2773021225000161 #ketamine #ketaminetherapy #ketamineassistedpsychotherapy #ketamineassistedtherapy #psychedelics #psychedelic #psychedelicassistedtherapy #neuroscience #recovery #12step #aa #alcoholicsanonymous #substanceusedisorder #cognitivebehavioraltherapy

https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/ Spotlight: Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide "The deployment of mesoscale brain-wide fluctuation analysis unveils the complex, multiregional neural orchestration underlying ketamine’s rapid antidepressant effects, a blueprint for future therapeutic innovation... insights gained from this research hold transformative promise..." #ketamine #ketaminetherapy #psychedelic #psychedelics #psychedelicresearch #neuroscience #psychiatry #mentalhealth

"For All We Know" by Mike Fiorito (@mike3fio) is a thought-provoking novel exploring life's big questions through a young protagonist navigating a chaotic "World of Wonder." The book blends music, psychedelics, and existential themes, encouraging readers to reflect on reality and consciousness.
Full review: https://www.goodreads.com/book/show/204866973-for-all-we-know

#ForAllWeKnow #MikeFiorito #BookReview #Goodreads #ThoughtProvoking #Consciousness #Philosophy #BookRecommendation #WesternCivilization #RealityAndWonder #UFO #Psychedelics
#authorinstagram #UAP #phenomenon

60 years ago yesterday (probably), jerry garcia's 1st LSD trip, according to a bunch of his pals i interviewed for @mojomagazine.bsky.social 10 years ago, just a few days before the 1st warlocks gig. https://archive.org/details/mojo-june-2015/page/66/mode/2up #deadfreaksunite #psychedelics #GratefulDead

"#Psychedelics – like dancing, drumming, darkness and other psychotropic drugs – push #shamans into states where they and their communities believe them to access otherworldly powers. This contrasts with the western clinical application, where psychedelics are administered like medicine and used to break down patients’ harmful patterns of thought."

The article is a little confusing. It seems to question the #ancientorigins of #psychedelicuse, but the presented evidences are quite weak.

https://www.theguardian.com/science/2025/may/01/the-ancient-psychedelics-myth-people-tell-tourists-the-stories-they-think-are-interesting-for-them

Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide - SCIENMAG https://apple.news/AUoWZT7pvRl-hZuRBVO6HNg #ketamine #ketaminetherapy #neuroscience #depression #mentalhealth #psychedelic #psychedelics #psychedelicresearch

https://pubmed.ncbi.nlm.nih.gov/40311741/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414 Beyond surgery: Repurposing anesthetics for treatment of central nervous system disorders (Mielko, et al, 2025) #ketamine #ketaminetherapy #psychedelic #psychedelics

https://pubmed.ncbi.nlm.nih.gov/40311814/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414 Glutamate plus glutamine to GABA ratio as a predictor of ketamine response in treatment-resistant depression: A double-blind, randomized, open-label extension study (Ohtani, et al 2025) #ketamine #ketaminetherapy #psychedelic #psychedelics #glutamate #brains #depression #mentalhealth