#Iowa House passes bill to establish state #psilocybin program https://iowacapitaldispatch.com/2025/04/21/iowa-house-passes-bill-to-establish-state-psilocybin-program/
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Happy 4/20 for does who celebrate!
Today marks the day after Bicycle Day, celebrated on April 19th to honor Albert Hofmann’s first intentional LSD trip and bike ride home in Basel, Switzerland. Now, on April 20th, we celebrate 420, a day dedicated to cannabis culture and community.
Enjoy the spirit of exploration and consciousness expansion that both days represent, whether on two wheels or with green leaves in hand. Stay safe and mindful in your journeys!
Linux.PizzaErik L. Midtsveen 🏴🏳️🌈🇳🇴 (@midtsveen@social.linux.pizza)🚲 Happy #BicycleDay!
Trip safely, practice harm reduction, and pay attention to your set and setting.
Today marks 82 years since Albert Hofmann, a Swiss chemist, intentionally took LSD and experienced its effects while riding his bike home in Basel, Switzerland.
DoubleBlind has a great video explaining Bicycle Day and why it’s celebrated:
- https://www.youtube.com/watch?v=InD5_Ml1OxQ
#AlbertHofmann #Hofmann #LSD #Psilocybin #LibertyCap #Shrooms #Bicycle #Switzerland #Basel
Replied in thread
Yes, I celebrate 4/19 instead of 4/20.
Weed is cool, but LSD hits differently.
Happy #BicycleDay!
Trip safely, practice harm reduction, and pay attention to your set and setting.
Today marks 82 years since Albert Hofmann, a Swiss chemist, intentionally took LSD and experienced its effects while riding his bike home in Basel, Switzerland.
DoubleBlind has a great video explaining Bicycle Day and why it’s celebrated:
Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus (Pałasz, et al, 2025) https://pubmed.ncbi.nlm.nih.gov/40243003/ #ketamine #psilocybin #psychedelics #psychedelic "results suggest for the first time that selected psychedelics may enhance the signaling of 5-HT2A receptors or inhibit NMDA receptor activity, affecting neuropeptide signaling and serotonin transmission in the rat hypothalamus, which may contribute to better understanding of psychedelic action in the brain
PubMedPsilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus - PubMedThese results suggest for the first time that selected psychedelics may enhance the signaling of 5-HT2A receptors or inhibit NMDA receptor activity, affecting neuropeptide signaling and serotonin transmission in the rat hypothalamus, which may contribute to a better understanding of psychedelic acti …
Today at Princeton University! Prof. Sam Wang discusses his laboratory research on the positive effects of #psilocybin on learning and neuronal growth. Thursday April 17, 6:30 PM, 101 Icahn Neuroscience building
Long-term Follow-up of Psilocybin-facilitated Smoking Cessation (2018) https://flip.it/Ne0xRf #cognitivebehavioraltherapy #smokingcessation #psilocybin #psychedelic #psychedelics #psychedelicassistedpsychotherapy #psychedelicresearch
Have you explored psychedelics as a tool for self-healing or personal growth?
“The mushroom was more alive and vibrant”: Patient reports of synthetic versus organic forms of psilocybin (Kryskow, et al, 2024) #psychedelic #plantmedicines #psilocybin #mushrooms #ketamine #mdma #lsd #ayahausca #lsd #dmt https://akjournals.com/view/journals/2054/8/3/article-p303.xml
SHROOM TO GROW: First Colorado psychedelic mushroom 'centers' poised to open
‘People can change hard-set habits. They can become unstuck. They can see things in new ways’
Sentinel Colorado · SHROOM TO GROW: First Colorado psychedelic mushroom ‘centers’ poised to open
SHROOM TO GROW: First Colorado psychedelic mushroom 'centers' poised to open
‘People can change hard-set habits. They can become unstuck. They can see things in new ways’
Sentinel Colorado · SHROOM TO GROW: First Colorado psychedelic mushroom ‘centers’ poised to open
#Trauma #psilocybin #brain #injury #treatment
www.sciencealert.com/psilocybin-p...
https://www.sciencealert.com/psilocybin-put-rat-brains-back-together-after-mild-head-trauma
ScienceAlert · Psilocybin Put Rat Brains 'Back Together' After Mild Head TraumaScientists are investigating whether the psychedelic ingredient in magic mushrooms can put a brain 'back together' after head injuries.
https://www.researchgate.net/publication/389438683_Prolonged_adverse_effects_from_repeated_psilocybin_use_in_an_underground_psychedelic_therapy_training_program_a_case_report Prolonged adverse effects from repeated psilocybin use in an underground psychedelic therapy training program: a case report (Perna, et al, 2025) #psilocybin #psychedelic #psychedelics #plantmedicine
Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity.
This ‘fundamental’ study into the effects of #psilocin on human neurons: https://elifesciences.org/reviewed-preprints/104006?utm_source=mastodon&utm_medium=social&utm_campaign=organic
"If it could be proven that the church was built on the foundation of holy fungi, not only would figures like Allegro be vindicated — psychedelics, too, could no longer be considered so taboo."
John Last for The Long Now Foundation: https://longreads.com/2025/03/11/is-god-a-mushroom/
https://pubmed.ncbi.nlm.nih.gov/40064389/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250311002448&v=2.18.0.post9+e462414 Current evidence for the role of rapid-acting antidepressants (RAAD) in bipolar depression? A perspective and plan for action (Repple, et al, 2025) #ketamine #psilocybin #5meodmt #bipolardepression #psychedelic #psychedelics #psychedelicresearch #mentalhealth
I wonder how long it will be until the Trump regime puts a halt to this type of research.
#psilocybin #brain #HeadTrauma #research
https://www.sciencealert.com/psilocybin-put-rat-brains-back-together-after-mild-head-trauma
ScienceAlert · Psilocybin Put Rat Brains 'Back Together' After Mild Head TraumaScientists are investigating whether the psychedelic ingredient in magic mushrooms can put a brain 'back together' after head injuries.
Replied in thread
"To test this idea, researchers gave what they describe as 'bump on head, ice pack' injuries to 16 adult female rats without anesthesia for three days in a row. Half an hour after each of the daily injuries, half the rats received an injection of psilocybin."
An unusual female-only study.
Hope it still works if treatment is delayed.
~
"The authors also noticed the rats treated with psilocybin showed reduced hyper-reactivity to CO2 following their head injuries and 'dramatic' differences in their functional connectivity."
Very interesting!
Psilocybin Put Rat Brains 'Back Together' After Mild Head Trauma
https://www.sciencealert.com/psilocybin-put-rat-brains-back-together-after-mild-head-trauma
ScienceAlert · Psilocybin Put Rat Brains 'Back Together' After Mild Head TraumaScientists are investigating whether the psychedelic ingredient in magic mushrooms can put a brain 'back together' after head injuries.